Colorectal Cancer Organoid-Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses
Henner F Farin, Mohammed H Mosa #, Benardina Ndreshkjana #, Britta M Grebbin #, Birgit Ritter #, Constantin Menche, Kilian B Kennel, Paul K Ziegler, Lili Szabó, Julia Bollrath, Dietmar Rieder, Birgitta E Michels, Alena Kress, Müge Bozlar, Tahmineh Darvishi, Sara Stier, Ivan-Maximilano Kur, Katrin Bankov, Rebecca Kesselring, Stefan Fichtner-Feigl, Bernhard Brüne, Thorsten O Goetze, Salah-Eddin Al-Batran, Christian H Brandts, Wolf O Bechstein, Peter J Wild, Andreas Weigert, Susanne Müller, Stefan Knapp, Zlatko Trajanoski, Florian R Greten. (# contributed equally)
Cancer Discov. 2023 Oct 5;13(10):2192-2211; doi: 10.1158/2159-8290.CD-23-0050

Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids
Svenja Wiechmann, Pierre Maisonneuve, Britta M Grebbin, Meike Hoffmeister, Manuel Kaulich, Hans Clevers, Krishnaraj Rajalingam, Igor Kurinov, Henner F Farin, Frank Sicheri, Andreas Ernst
J Biol Chem. 2020 Apr 3;295(14):4526-4540; doi: 10.1074/jbc.RA119.011025

Human colon organoids reveal distinct physiologic and oncogenic Wnt responses
Michels BE, Mosa MH, Grebbin BM, Yepes D, Darvishi T, Hausmann J, Urlaub H, Zeuzem S, Kvasnicka HM, Oellerich T, Farin HF.
J Exp Med. 2019 Mar 4;216(3):704-720; doi: 10.1084/jem.20180823

Arginin-methylation regulates MEIS2 subcellular localization to modulate neuronal differentiation of adult SVZ progenitors
Schramm J, Anders-Maurer M, Grebbin BM, Hau AC, Kallenborn-Gerhardt W, Behrends C and Schulte D.
Stem Cell Reports. 2018 Apr 10;10(4):1184-1192; doi: 10.1016/j.stemcr.2018.03.010

MEIS homeodomain proteins facilitate PARP1/ARTD1-mediated eviction of histone H1
Hau AC, Grebbin BM, Agoston Z, Anders-Maurer M, Müller T, Groß A, Kolb J, Langer JD, Döring C, Schulte D.
J Cell Biol. 2017 Sep 4;216(9):2715-2729; doi: 10.1083/jcb.201701154

Astrocytic Calcium Waves Signal Brain Injury to Neural Stem and Progenitor Cells
Kraft A, Jubal ER, von Laer R, Döring C, Rocha A, Grebbin M, Zenke M, Kettenmann H, Stroh A, Momma S.
Stem Cell Reports. 2017 Mar 14;8(3):701-714; doi: 10.1016/j.stemcr.2017.01.009

PBX1 as Pioneer Factor: A Case Still Open
Grebbin BM, Schulte D.
Front Cell Dev Biol. 2017 Feb 14;5:9; doi: 10.3389/fcell.2017.00009

YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis
Taniguchi K, Moroishi T, de Jong PR, Krawczyk M, Grebbin BM, Luo H, Xu RH, Golob-Schwarzl N, Schweiger C, Wang K, Di Caro G, Feng Y, Fearon ER, Raz E, Kenner L, Farin HF, Guan KL, Haybaeck J, Datz C, Zhang K, Karin M.
Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1643-1648; doi:10.1073/pnas.1620290114

Pbx1 is required for adult subventricular zone neurogenesis
Grebbin BM, Hau AC, Groß A, Anders-Maurer M, Schramm J, Koss M, Wille C, Mittelbronn M, Selleri L and Schulte D.
Development, 2016 Jul;143(13):2298-91; doi: 10.1242/dev.128033

Meis2 is a Pax6 co-factor in neurogenesis and dopaminergic periglomerular fate specification in the adult olfactory bulb
Agoston Z, Heine P, Brill MS, Grebbin BM, Hau AC, Kallenborn-Gerhardt W, Schramm J, Götz M, Schulte D.; .(joint first author)
Development, 2014 Jan;141(1):28-38; doi: 10.1242/dev.097295